Advancing drug discovery for glomerulopathies using stem-cell-derived kidney models
Author:
Funder
Duke University
National Science Foundation
Whitehead Foundation
National Institutes of Health
Alfred P. Sloan Foundation
Publisher
Elsevier BV
Subject
Pharmacology,Toxicology
Reference16 articles.
1. Stem cell therapies in kidney diseases: progress and challenges;Rota;Int. J. Mol. Sci.,2019
2. Mechanisms of podocyte detachment, podocyturia, and risk of progression of glomerulopathies;Trimachi;Kidney Dis.,2020
3. Defining the variety of cell types in developing and adult human kidneys by single-cell RNA sequencing;Schumacher;npj Regen. Med.,2021
4. The application of iPSC-derived kidney organoids and genome editing in kidney disease modeling;Traitteur;iPSCs State Sci.,2022
5. Drug-induced nephrotoxicity: pathogenic mechanisms, biomarkers and prevention strategies;Wu;Curr. Drug Metab.,2018
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1. Kidney Disease Modeling with Organoids and Organs-on-Chips;Annual Review of Biomedical Engineering;2024-07-03
2. An ultrathin membrane mediates tissue-specific morphogenesis and barrier function in a human kidney chip;Science Advances;2024-06-07
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