In vivo Target Residence Time and Kinetic Selectivity: The Association Rate Constant as Determinant

Author:

de Witte Wilhelmus E.A.,Danhof Meindert,van der Graaf Piet H.,de Lange Elizabeth C.M.

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

Reference39 articles.

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4. Pharmacology of JNJ-37822681, a specific and fast-dissociating D2 antagonist for the treatment of schizophrenia;Langlois;J. Pharmacol. Exp. Ther.,2012

5. Does fast dissociation from the dopamine D2 receptor explain the action of atypical antipsychotics?. A new hypothesis;Kapur;Am. J. Psychiatry,2001

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