Genetically engineered mouse models of PI3K signaling in breast cancer

Author:

Klarenbeek Sjoerd,van Miltenburg Martine H.,Jonkers Jos

Funder

European Union

Top Institute (TI) Pharma

TI Center for Translational Molecular Medicine (CTMM)

Netherlands Organization for Scientific Research (NWO)

Cancer Systems Biology Center and the Dutch Cancer Society (KWF)

Publisher

Wiley

Subject

Cancer Research,Genetics,Molecular Medicine,General Medicine,Oncology

Reference151 articles.

1. Delayed mammary gland involution in MMTV-AKT1 transgenic mice;Ackler;Oncogene,2002

2. Cooperation between Pik3ca and p53 mutations in mouse mammary tumor formation;Adams;Cancer Res.,2011

3. Subtle variations in Pten dose determine cancer susceptibility;Alimonti;Nat. Genet.,2010

4. Phase I study of everolimus plus weekly paclitaxel and trastuzumab in patients with metastatic breast cancer pretreated with trastuzumab;Andre;J. Clin. Oncol.,2010

5. TAMRAD: a GINECO randomized phase II trial of everolimus in combination with tamoxifen versus tamoxifen alone in patients (pts) with hormone-receptor positive, HER2 negative metastatic breast cancer (MBC) with prior exposure to aromatase inhibitors (AI);Bachelot;Cancer Res.,2011

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