Pre-clinical efficacy of PU-H71, a novel HSP90 inhibitor, alone and in combination with bortezomib in Ewing sarcoma-Reference-Cited by-同舟云学术

Pre-clinical efficacy of PU-H71, a novel HSP90 inhibitor, alone and in combination with bortezomib in Ewing sarcoma

Published:2013-12-15 Issue:2 Volume:8 Page:323-336
ISSN:1574-7891
Container-title:Molecular Oncology
language:en
Short-container-title:

Author:

Ambati Srikanth R.,Lopes Eloisi Caldas,Kosugi Kohji,Mony Ullas,Zehir Ahmet,Shah Smit K.,Taldone Tony,Moreira Andre L.,Meyers Paul A.,Chiosis Gabriela,Moore Malcolm A.S.

Publisher

Wiley

Subject

Cancer Research,Genetics,Molecular Medicine,General Medicine,Oncology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1016/j.molonc.2013.12.005/fullpdf

Reference50 articles.

1. Hsp90 inhibitors deplete key anti-apoptotic proteins in pediatric solid tumor cells and demonstrate synergistic anticancer activity with cisplatin;Bagatell;Int. J. Cancer,2005

2. Phase I pharmacokinetic and pharmacodynamic study of 17-N-allylamino-17-demethoxygeldanamycin in pediatric patients with recurrent or refractory solid tumors: a pediatric oncology experimental therapeutics investigators consortium study;Bagatell;Clin. Cancer Res.,2007

3. DNA-binding and transcriptional activation properties of the EWS-FLI-1 fusion protein resulting from the t(11;22) translocation in Ewing sarcoma;Bailly;Mol. Cell. Biol.,1994

4. Contribution of MEK/MAPK and PI3-K signaling pathway to the malignant behavior of Ewing's sarcoma cells: therapeutic prospects;Benini;Int. J. Cancer,2003

5. Mutant conformation of p53 translated in vitro or in vivo requires functional HSP90;Blagosklonny;Proc. Natl. Acad. Sci.,1996

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