WNT-5A triggers Cdc42 activation leading to an ERK1/2 dependent decrease in MMP9 activity and invasive migration of breast cancer cells

Author:

Prasad Chandra Prakash,Chaurasiya Shivendra Kumar,Axelsson Lena,Andersson Tommy

Funder

Swedish Cancer Foundation

Swedish Research Council

Söderberg Foundations

Skåne University Hospital Research Foundations

Gunner Nilsson's Cancer Foundation

Publisher

Wiley

Subject

Cancer Research,Genetics,Molecular Medicine,General Medicine,Oncology

Reference69 articles.

1. Raf-induced MMP9 disrupts tissue architecture of human breast cells in three-dimensional culture and is necessary for tumor growth in vivo;Beliveau;Genes Dev.,2010

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3. Wnt signaling: a common theme in animal development;Cadigan;Genes Dev.,1997

4. Activation of MAP kinases by calcium-dependent and calcium-independent pathways. Stimulation by thapsigargin and epidermal growth factor;Chao;J. Biol. Chem.,1992

5. Extracellular signal-regulated kinase signaling pathway regulates breast cancer cell migration by maintaining slug expression;Chen;Cancer Res.,2009

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