Cancer-pain intractable to high-doses systemic opioids can be relieved by intraspinal local anaesthetic plus an opioid and an alfa2-adrenoceptor agonist
Author:
Affiliation:
1. Department of Pain Management and Research , Oslo University Hospital , Oslo Norway
2. Department of Anaesthesiology , Oslo University Hospital , Oslo Norway
3. University of Oslo , Faculty of Medicine , Oslo , Norway
Publisher
Walter de Gruyter GmbH
Subject
Anesthesiology and Pain Medicine,Neurology (clinical)
Link
https://www.degruyter.com/document/doi/10.1016/j.sjpain.2017.06.001/pdf
Reference7 articles.
1. Kiehelä L, Hamunen K, Heiskanen T. Spinal analgesia for severe cancer pain: a retrospective analysis of 60 patient. Scand J Pain 2017;16:140–5.
2. Mastenbroek TC, Kramp-Hendriks BJ, Kallewaard JW, Vonk JM. Multimodal intrathecal analgesia in refractory cancer pain. Scand J Pain 2017;14:39–43.
3. Breivik H. Terminal cancer pain intractable by conventional pain management can be effectively relieved by intrathecal administration of a local anaesthetic plus an opioid and an alfa2 -agonist into the cerebro-spinal-fluid. Scand J Pain 2017;14:71–3.
4. Niemi G, Breivik H. Adrenaline markedly improves thoracic epidural analgesia produced by a low-dose infusion of bupivacaine, fentanyl and adrenaline after major surgery. A randomised, double-blind, cross-over study with and without adrenaline. Acta Anaesthesiol Scand 1998;42:897–909.
5. Breivik H. Local anesthetic blocks and epidurals. In: McMahon SB, Koltzenburg M, Tracey I, Turk DC, editors. Wall and Melzack’s textbook of pain. sixth ed. Philadelphia: Elsevier; 2013. p. 523–37 [chapter 37].
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