A novel cell source for therapy of knee osteoarthritis using atelocollagen microsphere-adhered adipose-derived stem cells: Impact of synovial fluid exposure on cell activity

Author:

Sakamoto TakuyaORCID,Fuku Atsushi,Horie TetsuhiroORCID,Kitajima Hironori,Nakamura Yuka,Tanida Ikuhiro,Sunami Hiroshi,Hirata Hiroaki,Tachi Yoshiyuki,Iida YasuoORCID,Yamada Sohsuke,Yamamoto Naoki,Shimizu YusukeORCID,Ishigaki Yasuhito,Ichiseki Toru,Kaneuji Ayumi,Osawa Satoshi,Kawahara Norio

Funder

Kanazawa Medical University

Shibuya Science Culture and Sports Foundation

Ministry of Education, Culture, Sports, Science and Technology

Japan Society for the Promotion of Science

Publisher

Elsevier BV

Reference49 articles.

1. Non-surgical management of knee osteoarthritis: comparison of ESCEO and OARSI 2019 guidelines;Arden;Nat Rev Rheumatol,2021

2. Cellular therapy and tissue engineering for cartilage repair;Zelinka;Osteoarthritis Cartilage,2022

3. Exosomes derived from human embryonic mesenchymal stem cells promote osteochondral regeneration;Zhang;Osteoarthritis Cartilage,2016

4. The paracrine effect of adipose-derived stem cells inhibits osteoarthritis progression orthopedics and biomechanics;Kuroda;BMC Muscoskel Disord,2015

5. Safety and efficacy of the intra-articular injection of mesenchymal stem cells for the treatment of osteoarthritic knee: a 5-year follow-up study;Kim;Stem Cells Transl Med,2022

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