Synthesis and PET imaging of the benzodiazepine receptor tracer [N-methyl-11C]iomazenil

Author:

Baldwin Ronald M.,Horti Andrew G.,Bremner J.Douglas,Stratton Morgan D.,Dannals Robert F.,Ravert Hayden T.,Zea-Ponce Yolanda,Ng Chin K.,Dey Holley M.,Soufer Robert,Charney Dennis S.,Mazza Samuel M.,Sparks Richard B.,Stubbs James B.,Innis Robert B.

Publisher

Elsevier BV

Subject

Cancer Research,Radiology Nuclear Medicine and imaging,Molecular Medicine

Reference30 articles.

1. Central benzodiazepine receptors in human brain—estimation of regional Bmax and Kd values with positron emission tomography;Abadie;Eur. J. Pharmacol.,1992

2. SPECT measurement of benzodiazepine receptors in human brain with [123I]iomazenil: kinetic and equilibrium paradigms;Abi-Dargham;J. Nucl. Med.,1994

3. A comparison of methods for separation of [11C]Ro 15-1788 (flumazenil) from its metabolites in the blood of rabbits, baboons, and humans;Barre;Appl. Radiat., Isot.,1991

4. In vitro and in vivo evaluation of iodine-123 Ro 16-0154: a new imaging agent for SPECT investigations of benzodiazepine receptors;Beer;J. Nucl. Med.,1990

5. Tracer kinetic modeling of [C-11]iomazenil;Buck;J. Nucl. Med.,1994

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