Metabolic and pharmacokinetic considerations in the design of 2-phenyl substituted metyrapone derivatives: 2-methoxyphenylmetyrapone as a radioligand for functional diagnosis of adrenal pathology-Reference-Cited by-同舟云学术

Metabolic and pharmacokinetic considerations in the design of 2-phenyl substituted metyrapone derivatives: 2-methoxyphenylmetyrapone as a radioligand for functional diagnosis of adrenal pathology

Published:1995-11 Issue:8 Volume:22 Page:1067-1074
ISSN:0969-8051
Container-title:Nuclear Medicine and Biology
language:en
Short-container-title:Nuclear Medicine and Biology

Author:

Damani L.A.,Mitterhauser M.,Zolle I.,Lin G.,Oehler E.,Ho Y.P.

Publisher

Elsevier BV

Subject

Cancer Research,Radiology Nuclear Medicine and imaging,Molecular Medicine

Reference11 articles.

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2. Synthesis of N-oxide derivatives of metyrapone and their detection as in vitro metabolites;Crooks;J. Pharm. Pharmacol.,1981

3. Metabolism of metyrapone. 2-Chromatographic and mass spectral properties of the N-oxides of metyrapone and metyrapol;Damani;Biomed. Mass Spectrum.,1981

4. Structure-activity relationship study of the inhibition of adrenal cortical 11β-hydroxylase by new metyrapone analogues;Hays;J. Med. Chem.,1984

5. The binding of metyrapone to cytochrome. P-450 and its inhibitory action on liver microsomal mixed-function oxidase reactions;Hildebrandt;Biochem. J.,1971

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