NPC1-mTORC1 Signaling Couples Cholesterol Sensing to Organelle Homeostasis and Is a Targetable Pathway in Niemann-Pick Type C-Reference-Cited by-同舟云学术

登录注册会员服务联系我们

NPC1-mTORC1 Signaling Couples Cholesterol Sensing to Organelle Homeostasis and Is a Targetable Pathway in Niemann-Pick Type C

Published:2021-02 Issue:3 Volume:56 Page:260-276.e7
ISSN:1534-5807
Container-title:Developmental Cell
language:en
Short-container-title:Developmental Cell

Author:

Davis Oliver B.,Shin Hijai R.,Lim Chun-Yan,Wu Emma Y.,Kukurugya Matthew,Maher Claire F.,Perera Rushika M.,Ordonez M. Paulina,Zoncu Roberto

Funder

National Institutes of Health

Publisher

Elsevier BV

Subject

Developmental Biology,Cell Biology,General Biochemistry, Genetics and Molecular Biology,Molecular Biology

Reference101 articles.

1. Lysosomal metabolomics reveals V-ATPase- and mTOR-dependent regulation of amino acid efflux from lysosomes;Abu-Remaileh;Science,2017

2. Architecture of human Rag GTPase heterodimers and their complex with mTORC1;Anandapadamanaban;Science,2019

3. Cystinosin is a component of the vacuolar H+-ATPase-ragulator-rag complex controlling mammalian target of rapamycin complex 1 signaling;Andrzejewska;J. Am. Soc. Nephrol.,2016

4. Lysosomal disorders: from storage to cellular damage;Ballabio;Biochim. Biophys. Acta,2009

5. Ragulator is a GEF for the rag GTPases that signal amino acid levels to mTORC1;Bar-Peled;Cell,2012

Cited by 123 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Npc1 deficiency impairs microglia function via TREM2-mTOR signaling in Niemann-Pick disease type C;Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease;2024-12

2. Why make it if you can take it: review on extracellular cholesterol uptake and its importance in breast and ovarian cancers;Journal of Experimental & Clinical Cancer Research;2024-09-06

3. A new perspective on the regulation of glucose and cholesterol transport by mitochondria-lysosome contact sites;Frontiers in Physiology;2024-09-03

4. mTORC1 Signaling Inhibition Modulates Mitochondrial Function in Frataxin Deficiency;2024-08-07

5. Gaucher disease provides a unique window into Parkinson disease pathogenesis;Nature Reviews Neurology;2024-08-06

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号京ICP备18003416号-3