Itaconate uptake via SLC13A3 improves hepatic antibacterial innate immunity
Author:
Funder
National Natural Science Foundation of China
Excellent Young Scientists Fund
Youth Innovation Promotion Association of the Chinese Academy of Sciences
Publisher
Elsevier BV
Reference46 articles.
1. The immunomodulatory potential of the metabolite itaconate;Hooftman;Trends Immunol.,2019
2. Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production;Michelucci;Proc. Natl. Acad. Sci. USA,2013
3. Food fight: role of itaconate and other metabolites in antimicrobial defense;Luan;Cell Metab.,2016
4. Myeloid-derived itaconate suppresses cytotoxic CD8(+) T cells and promotes tumour growth;Zhao;Nat. Metab.,2022
5. Targeting IRG1 reverses the immunosuppressive function of tumor-associated macrophages and enhances cancer immunotherapy;Chen;Sci. Adv.,2023
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