Stabilization of Xist RNA Mediates Initiation of X Chromosome Inactivation

Author:

Sheardown Steven A,Duthie Sarah M,Johnston Colette M,Newall Alistair E.T,Formstone Emma J,Arkell Ruth M,Nesterova Tatyana B,Alghisi Gian-Carlo,Rastan Sohaila,Brockdorff Neil

Publisher

Elsevier BV

Subject

General Biochemistry, Genetics and Molecular Biology

Reference52 articles.

1. Loss of methylation activates Xist in somatic but not in embryonic cells;Beard;Genes Dev.,1995

2. Beddington, R.S.P. (1987). Isolation, culture and manipulation of postimplantation mouse embryos. In Mammalian Development: A Practical Approach M. Monk, ed. (Oxford: IRL Press), 43–69.

3. Characterization of a murine gene expressed from the inactive X chromosome;Borsani;Nature,1991

4. Conservation of position and exclusive expression of mouse Xist from the inactive X chromosome;Brockdorff;Nature,1991

5. The product of the mouse Xist gene is a 15 kb inactive X-specific transcript containing no conserved ORF and located in the nucleus;Brockdorff;Cell,1992

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