Safety, Pharmacokinetic, and Pharmacodynamic Evaluation After Single and Multiple Ascending Doses of a Novel Selective Androgen Receptor Modulator in Healthy Subjects-Reference-Cited by-同舟云学术

Safety, Pharmacokinetic, and Pharmacodynamic Evaluation After Single and Multiple Ascending Doses of a Novel Selective Androgen Receptor Modulator in Healthy Subjects

Published:2016-06 Issue:6 Volume:38 Page:1401-1416
ISSN:0149-2918
Container-title:Clinical Therapeutics
language:en
Short-container-title:Clinical Therapeutics

Author:

Bhattacharya Indranil,Tarabar Sanela,Liang Yali,Pradhan Vivek,Owens Jane,Oemar Barry

Publisher

Elsevier BV

Subject

Pharmacology (medical),Pharmacology

Reference17 articles.

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3. An orally active selective androgen receptor modulator is efficacious on bone, muscle, and sex function with reduced impact on prostate;Miner;Endocrinology,2007

4. Discovery of the selective androgen receptor modulator MK-0773 using a rational development strategy based on differential transcriptional requirements for androgenic anabolism versus reproductive physiology;Schmidt;J Biol Chem,2010

5. The selective androgen receptor modulator GTx-024 (enobosarm) improves lean body mass and physical function in healthy elderly men and postmenopausal women: results of a double-blind, placebo-controlled phase II trial;Dalton;J Cachexia Sarcopenia Muscle,2011

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