The anti-influenza drug oseltamivir evokes hypothermia in mice through dopamine D 2 receptor activation via central actions

Author:

Fukushima Akihiro,Fukui Arisa,Takemura Yuki,Maeda Yasuhiro,Ono Hideki

Funder

Musashino University

Publisher

Elsevier BV

Subject

Pharmacology,Molecular Medicine

Reference15 articles.

1. FDA review: Department of Health and Human Services, Public Health Service, Food and Drug Administration, Center for Drug Evaluation and Research, One-year post pediatric exclusivity postmarketing adverse event review, Drug: oseltamivir phosphate, ODS PID# D040223. http://www.fda.gov/ohrms/dockets/ac/05/briefing/2005-4180b_06_01_Tamiflu AE_reviewed.pdf. Published 2005.

2. Oseltamivir, an anti-influenza virus drug, produces hypothermia in mice;Ono;Biol Pharm Bull,2008

3. Reduction in sympathetic nerve activity as a possible mechanism for the hypothermic effect of oseltamivir, an anti-influenza virus drug, in normal mice;Ono;Basic Clin Pharmacol Toxicol,2013

4. Oseltamivir produces hypothermic and neuromuscular effects by inhibition of nicotinic acetylcholine receptor functions: comparison to procaine and bupropion;Fukushima;Eur J Pharmacol,2015

5. Nonclinical pharmacokinetics of oseltamivir and oseltamivir carboxylate in the central nervous system;Hoffmann;Antimicrob Agents Chemother,2009

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