SAR110894, a potent histamine H3-receptor antagonist, displays disease-modifying activity in a transgenic mouse model of tauopathy-Reference-Cited by-同舟云学术

SAR110894, a potent histamine H3-receptor antagonist, displays disease-modifying activity in a transgenic mouse model of tauopathy

Published:2016-11 Issue:4 Volume:2 Page:267-280
ISSN:2352-8737
Container-title:Alzheimer's & Dementia: Translational Research & Clinical Interventions
language:en
Short-container-title:Alzheimer's & Dementia: Translational Research & Clinical Interventions

Author:

Delay-Goyet Philippe¹,Blanchard Véronique¹,Schussler Nathalie¹,Lopez-Grancha Mati¹,Ménager Jean¹,Mary Véronique¹,Sultan Eric²,Buzy Armelle³,Guillemot Jean-Claude³,Stemmelin Jeanne¹,Bertrand Philippe¹,Rooney Thomas¹,Pradier Laurent¹,Barnéoud Pascal¹

Affiliation:

1. Neurodegeneration and Pain Unit; Sanofi R&D; Chilly-Mazarin France

2. Disposition, Safety and Animal Research; Sanofi R&D; Montpellier France

3. Translational Sciences Unit; Sanofi R&D; Chilly-Mazarin France

Publisher

Wiley

Subject

Psychiatry and Mental health,Clinical Neurology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1016/j.trci.2016.10.002/fullpdf

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4. Cellular phosphorylation of tau by GSK-3β influences tau binding to microtubules and microtubule organisation;Wagner;J Cell Sci,1996

5. Specific tau phosphorylation sites correlate with severity of neuronal cytopathology in Alzheimer's disease;Augustinack;Acta Neuropathol,2002

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