Alzheimer's Prevention Initiative Generation Program: Development of an APOE genetic counseling and disclosure process in the context of clinical trials-Reference-Cited by-同舟云学术

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Alzheimer's Prevention Initiative Generation Program: Development of an APOE genetic counseling and disclosure process in the context of clinical trials

Published:2019-01 Issue:1 Volume:5 Page:705-716
ISSN:2352-8737
Container-title:Alzheimer's & Dementia: Translational Research & Clinical Interventions
language:en
Short-container-title:Alzheimer's & Dementia: Translational Research & Clinical Interventions

Author:

Langlois Carolyn M.¹,Bradbury Angela²,Wood Elisabeth M.²,Roberts J. Scott³,Kim Scott Y.H.⁴,Riviere Marie‐Emmanuelle⁵,Liu Fonda⁶,Reiman Eric M.¹⁷⁸⁹¹⁰,Tariot Pierre N.¹,Karlawish Jason¹¹,Langbaum Jessica B.¹

Affiliation:

1. Banner Alzheimer's InstitutePhoenixAZUSA

2. Department of Medical Ethics and Health PolicyUniversity of PennsylvaniaPhiladelphiaPAUSA

3. Department of Health Behavior and Health EducationUniversity of Michigan School of Public HealthAnn ArborMIUSA

4. National Institutes of HealthBethesdaMDUSA

5. Novartis Pharma AGBaselSwitzerland

6. Novartis Pharmaceuticals CorporationEast HanoverNJUSA

7. Neurodegenerative Disease Research Center, Arizona State UniversityTempeAZUSA

8. Department of PsychiatryUniversity of Arizona School of Medicine – PhoenixPhoenixAZUSA

9. Department of PsychiatryUniversity of ArizonaTucsonAZUSA

10. Neurogenomics DivisionTranslational Genomics Research InstitutePhoenixAZUSA

11. Departments of Medicine, Medical Ethics and Health Policy, and NeurologyUniversity of PennsylvaniaPhiladelphiaPAUSA

Funder

Amgen

National Institute on Aging

National Institutes of Health

Alzheimer's Association

NIH Office of the Director

NINDS

Novartis

Banner Alzheimer's Foundation

Genentech

Roche

Fidelity Biosciences Research Initiative

GHR

NOMIS Foundation

Flinn Foundation

Arizona Department of Health Services

FBRI

NOMIS FOUNDATION

AstraZeneca

Avanir

Lilly

Lundbeck

Merck & Co

Takeda

Avid

Biogen

Elan

Functional Neuromodulation

Targacept

Arizona Alzheimer's Consortium

Novartis Pharma AG

Banner Alzheimer's Institute

GHR Foundation

Publisher

Wiley

Subject

Psychiatry and Mental health,Clinical Neurology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1016/j.trci.2019.09.013

Reference56 articles.

1. The worldwide costs of dementia 2015 and comparisons with 2010

2. Alzheimer's disease drug development pipeline: 2018

3. The Alzheimer's Prevention Initiative Autosomal‐Dominant Alzheimer's Disease Trial: A study of crenezumab versus placebo in preclinical PSEN1 E280A mutation carriers to evaluate efficacy and safety in the treatment of autosomal‐dominant Alzheimer's disease, including a placebo‐treated noncarrier cohort

4. Ethics of genetic and biomarker test disclosures in neurodegenerative disease prevention trials

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1. Advertisement by medical facilities as an opportunity route of APOE genetic testing in Japan: a website analysis;Journal of Community Genetics;2024-01-16

2. Interest in genetic susceptibility testing and disclosure of AD dementia risk in cognitively normal adults: a survey study;Alzheimer's Research & Therapy;2024-01-02

3. User and Usability Testing of a Web-Based Genetics Education Tool for Parkinson Disease: Mixed Methods Study;JMIR Bioinformatics and Biotechnology;2023-08-30

4. Refining Risk for Alzheimer’s Disease Among Heterozygous APOE ɛ4 Carriers;Journal of Alzheimer's Disease;2023-07-18

5. Biomarker disclosure protocols in prodromal Alzheimer's disease clinical trials;Alzheimer's & Dementia;2023-07-14

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