Two randomized controlled trials of SB742457 in mild-to-moderate Alzheimer's disease-Reference-Cited by-同舟云学术

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Two randomized controlled trials of SB742457 in mild-to-moderate Alzheimer's disease

Published:2015-05-06 Issue:1 Volume:1 Page:23-36
ISSN:2352-8737
Container-title:Alzheimer's & Dementia: Translational Research & Clinical Interventions
language:en
Short-container-title:Alzheimer's & Dementia: Translational Research & Clinical Interventions

Author:

Maher-Edwards Gareth¹,Watson Carolyn²,Ascher John²,Barnett Carly¹,Boswell Diane¹,Davies John¹,Fernandez Manuel³,Kurz Alexander⁴,Zanetti Orazio⁵,Safirstein Beth⁶,Schronen Juan Paul⁷,Zvartau-Hind Marina¹,Gold Michael²⁸

Affiliation:

1. Neurosciences; GlaxoSmithKline; Uxbridge Middlesex UK

2. Neurosciences; GlaxoSmithKline; Research Triangle Park NC USA

3. Neurology Department; Hospital Universitario Cruces, BioCruces Health Research Institute; Barakaldo-Vizcaya Spain

4. Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar; Technische Universität München; Munich Germany

5. Unità Operativa Alzheimer; IRCCS; Brescia Italy

6. MD Clinical; Hallandale Beach FL USA

7. Cape Trial Centre; Cape Town South Africa

8. Currently Global Therapeutic Area CNS; UCB Pharmaceuticals; Raleigh NC USA

Funder

GlaxoSmithKline

Publisher

Wiley

Subject

Psychiatry and Mental health,Clinical Neurology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1016/j.trci.2015.04.001/fullpdf

Reference29 articles.

1. 5-HT6 receptor antagonists as novel cognitive enhancing agents for Alzheimer's disease;Upton;Neurotherapeutics,2008

2. 5-HT(6) receptor and cognition;Codony;Curr Opin Pharmacol,2011

3. 5-HT6 receptor antagonists as potential therapeutics for cognitive impairment;Rosse;Curr Top Med Chem,2010

4. SB-399885 is a potent, selective 5-HT6 receptor antagonist with cognitive enhancing properties in aged rat water maze and novel object recognition models;Hirst;Eur J Pharmacol,2006

5. SB-742457 and donepezil in Alzheimer disease: a randomized, placebo-controlled study;Maher-Edwards;Int J Geriatr Psychiatry,2011

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