Disease severity and minimal clinically important differences in clinical outcome assessments for Alzheimer's disease clinical trials
Author:
Affiliation:
1. Eli Lilly and Company, Lilly Corporate CenterIndianapolisINUSA
2. Analysis Group, Inc.BostonMAUSA
Funder
National Institute on Aging
National Institutes of Health
Eli Lilly and Company
NIA
NIH
Publisher
Wiley
Subject
Psychiatry and Mental health,Clinical Neurology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1016/j.trci.2019.06.005
Reference19 articles.
1. Systematic Review of Measures of Clinical Significance Employed in Randomized Controlled Trials of Drugs for Dementia
2. A point of minimal important difference (MID): a critique of terminology and methods
3. Measurement of health status
4. Green Park Collaborative Evidence guidance document: design of clinical studies of pharmacologic therapies for Alzheimer's disease Center for Medical Technology Policy.2013. Available at:http://www.cmtpnet.org/docs/resources/GPC_Evidence_Guidance_Document_‐_Alzheimers_Disease.pdf. Accessed September 10 2018.
5. L.Webster D.Groskreutz A.Grinbergs‐Saull R.Howard J.T.O'Brien andG.Mountain et al.Core outcome measures for interventions to prevent or slow the progress of dementia for people living with mild to moderate dementia: systematic review and consensus recommendations 2017. Available at:https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0179521 2017Accessed September 10 2018.
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