T1R2 receptor-mediated glucose sensing in the upper intestine potentiates glucose absorption through activation of local regulatory pathways

Author:

Smith Kathleen,Karimian Azari Elnaz,LaMoia Traci E.,Hussain Tania,Vargova VeronikaORCID,Karolyi Katalin,Veldhuis Paula P.,Arnoletti Juan Pablo,de la Fuente Sebastian G.,Pratley Richard E.,Osborne Timothy F.,Kyriazis George A.

Funder

National Institutes of Health

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology

Reference55 articles.

1. The gut as a sensory organ;Furness;Nature Reviews Gastroenterology & Hepatology,2013

2. Enteroendocrine cells: chemosensors in the intestinal epithelium;Gribble;Annual Review of Physiology,2016

3. Physiology of proglucagon peptides: role of glucagon and GLP-1 in health and disease;Sandoval;Physiological Reviews,2015

4. Incretin-based therapies for type 2 diabetes mellitus;Lovshin;Nature Reviews Endocrinology,2009

5. Impaired intestinal proglucagon processing in mice lacking prohormone convertase 1;Ugleholdt;Endocrinology,2004

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