Optimized GIP analogs promote body weight lowering in mice through GIPR agonism not antagonism
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology
Reference46 articles.
1. Semaglutide and cardiovascular outcomes in patients with type 2 diabetes;Marso;New England Journal of Medicine,2016
2. Liraglutide and cardiovascular outcomes in type 2 diabetes;Marso;New England Journal of Medicine,2016
3. Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus;Nauck;Journal of Clinical Investigation,1993
4. Four weeks of near-normalisation of blood glucose improves the insulin response to glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes;Hojberg;Diabetologia,2009
5. Unimolecular dual incretins maximize metabolic benefits in rodents, monkeys, and humans;Finan;Science Translational Medicine,2013
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