SORLA mediates endocytic uptake of proIAPP and protects against islet amyloid deposition

Author:

Shih Alexis Z.L.ORCID,Chen Yi-ChunORCID,Speckmann ThiloORCID,Søndergaard EsbenORCID,Schürmann AnnetteORCID,Verchere C. BruceORCID,Willnow Thomas E.ORCID

Funder

Novo Nordisk Foundation

JDRF Canada

Alzheimer Forschung Initiative e V

European Research Council

Canadian Institutes of Health Research

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology

Reference54 articles.

1. Islet prohormone processing in health and disease;Chen;Diabetes, Obesity and Metabolism,2018

2. Processing of pro-islet amyloid polypeptide in the constitutive and regulated secretory pathways of β cells;Marzban;Molecular Endocrinology,2005

3. The role of amylin in the control of energy homeostasis;Lutz;American Journal of Physiology - Regulatory, Integrative and Comparative Physiology,2010

4. Islet amyloid polypeptide in the islets of Langerhans: friend or foe?;Gebre-Medhin;Diabetologia,2000

5. Islet amyloid: a critical entity in the pathogenesis of type 2 diabetes;Hull;Journal of Clinical Endocrinology and Metabolism,2004

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