The type 2 diabetes gene product STARD10 is a phosphoinositide-binding protein that controls insulin secretory granule biogenesis

Author:

Carrat Gaelle R.ORCID,Haythorne Elizabeth,Tomas Alejandra,Haataja Leena,Müller Andreas,Arvan Peter,Piunti Alexandra,Cheng Kaiying,Huang Mutian,Pullen Timothy J.,Georgiadou Eleni,Stylianides Theodoros,Amirruddin Nur Shabrina,Salem Victoria,Distaso Walter,Cakebread Andrew,Heesom Kate J.,Lewis Philip A.ORCID,Hodson David J.,Briant Linford J.,Fung Annie C.H.ORCID,Sessions Richard B.,Alpy Fabien,Kong Alice P.S.ORCID,Benke Peter I.,Torta Federico,Teo Adrian Kee Keong,Leclerc Isabelle,Solimena Michele,Wigley Dale B.,Rutter Guy A.

Funder

Wellcome Trust Senior Investigator

MRC Programme

Experimental Challenge

Diabetes UK

Imperial Confidence in Concept

Royal Society Wolfson Research

NIH

Wellcome Trust Institutional Support Award, and MRC

European Research Council

Innovative Medicines Initiative 2 Joint Undertaking

European Union’s Horizon 2020

EFPIA

MRC

Medical Research Council and Cancer Research UK

Wellcome Trust

BBSRC

Wellcome Trust Multi-User Equipment

German Ministry for Education and Research

German Centre for Diabetes Research

NUS Research Scholarship

(IMCB), A∗STAR

CMCB Technology

Sun Pharmaceuticals

Servier

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology

Reference80 articles.

1. The role of assembly in insulin's biosynthesis;Dodson;Current Opinion in Structural Biology,1998

2. Pancreatic β-cell identity, glucose sensing and the control of insulin secretion;Rutter;Biochemical Journal,2015

3. Beta cell connectivity in pancreatic islets: a type 2 diabetes target?;Rutter;Cellular and Molecular Life Sciences,2015

4. Local and regional control of calcium dynamics in the pancreatic islet;Rutter;Diabetes, Obesity and Metabolism,2017

5. Beta cell hubs dictate pancreatic islet responses to glucose;Johnston;Cell Metabolism,2016

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