Autocrine negative feedback regulation of lipolysis through sensing of NEFAs by FFAR4/GPR120 in WAT

Author:

Husted Anna SofieORCID,Ekberg Jeppe H.ORCID,Tripp EmmaORCID,Nissen Tinne A.D.ORCID,Meijnikman Stijn,O'Brien Shannon L.,Ulven TrondORCID,Acherman YairORCID,Bruin Sjoerd C.,Nieuwdorp Max,Gerhart-Hines Zach,Calebiro Davide,Dragsted Lars O.,Schwartz Thue W.ORCID

Funder

Challenge Grant

Immunometabolism Grant

Novo Nordisk Foundation

The Novo Nordisk Foundation Center for Basic Metabolic Research

Carlsberg Foundation

Wellcome Trust Senior Research Fellowship

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology

Reference55 articles.

1. Free fatty acids as feedback regulators of adenylate cyclase and cyclic 3':5'-AMP accumulation in rat fat cells;Fain;Journal of Biological Chemistry,1975

2. The role of free fatty acids in the regulation of lipolysis by human adipose tissue cells;Burns;Metabolism,1978

3. Suppression of adipose lipolysis by long-chain fatty acid analogs;Kalderon;The Journal of Lipid Research,2012

4. The influence of lipolysis on energy metabolism of isolated fat cells;Jeanrenaud;Hormone and Metabolic Research,1970

5. GPCR-mediated signaling of metabolites;Husted;Cell Metabolism,2017

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