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Opposing effects of prostaglandin E 2 receptors EP3 and EP4 on mouse and human β-cell survival and proliferation

  • Published:2017-06 Issue:6 Volume:6 Page:548-559
  • ISSN:2212-8778
  • Container-title:Molecular Metabolism
  • language:en
  • Short-container-title:Molecular Metabolism

Author:

Carboneau Bethany A.,Allan Jack A.,Townsend Shannon E.,Kimple Michelle E.,Breyer Richard M.,Gannon Maureen

Funder

VA

Training Program in Stem Cell and Regenerative Developmental Biology

Vanderbilt Short Term Research Training Program

National Institutes of Health

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology

Reference58 articles.

1. High fat diet regulation of beta-cell proliferation and beta-cell mass;Golson;The Open Endocrinology Journal,2010

2. Protein-coupled receptors as potential targets for treatment of type 2 diabetes;Ahren;Nature Reviews Drug Discovery,2009

3. An overview on GPCRs and drug discovery: structure-based drug design and structural biology on GPCRs;Lundstrom;Methods in Molecular Biology,2009

4. Gastrointestinal hormones and the regulation of beta-cell mass;Lavine;Annals of the New York Academy of Sciences,2010

5. New therapeutic strategies for the treatment of type 2 diabetes mellitus based on incretins;Gallwitz;The Review of Diabetic Studies,2005
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