Author:
Leonard* John,Fearnley Stephen P.,Hague Andrew B.,Wong Gordon,Jones Martin F.
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference11 articles.
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2. A short synthesis of apoyohimbines via a sulfolene based intramolecular Diels-Alder reaction
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4. Sulpholene 1 is commercially available from Fluka Chemical Company, or can be prepared; McIntosh, J.M.; Sieler, R.A. J. Org. Chem., 1978, 43, 4431–4433, and Can. J. Chem., 1978, 56, 226–231. We have also developed a simple large scale ‘one-pot’ procedure for the preparation of 1 which will be published shortly.
5. a) Chou, T-S.; Tso, H-H.; Chang, L-J. Chem. Commun., 1985, 236–237; b) Chou, T-S.; Lee, S-J.; Yao, N-K. Tetrahedron, 1989, 45, 4113–4124; c) Lee, S-J.; Chou, T-S. Chem. Commun., 1988, 1188–1189; d) Chou, T-S.; Tso, H-H.; Chang, L-J. Chem. Commun., 1984, 1323–1324.
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