Stereocontrolled approach to acromelic acids
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference15 articles.
1. Isolation: acromelic acids A and B: (a) Konno, K.; Shirahama, H.; Matsumoto, T. Tetrahedron Lett. 1983, 24, 939; (b) Konno, K.; Hashimoto, K.; Ohfune, Y.; Shirahama, H.; Matsumoto, T. J. Am. Chem. Soc. 1988, 110, 4807; acromelic acids C, D, E: (c) Fushiya, S.; Satou, S.; Kera, Y.; Nozoe, S. Heterocycles 1992, 34, 1277; (d) Fushiya, S.; Satou, S.; Kanazawa, T.; Kusano, G.; Nozoe, S. Tetrahedron Lett. 1990, 31, 3901.
2. Acromelic acid, a novel excitatory amino acid from a poisonous mushroom: effects on the crayfish neuromuscular junction
3. Synthesis: acromelic acid A: (a) Ref. 1a; (b) Ref. 1b; (c) Takano, S.; Iwabuchi, Y.; Ogasawara, K. J. Am. Chem. Soc. 1987, 109, 5523; (d) Baldwin, J. E.; Li, C.-S. J. Chem. Soc., Chem. Commun. 1988, 261; acromelic acid B: (e) Ref. 1a; (f) Ref. 1b; (g) Takano, S.; Tomita, S.; Iwabuchi, Y.; Ogasawara, K. Heterocycles 1989, 29, 1473; (h) Horikawa, M.; Hashimoto, K.; Shirahama, H. Tetrahedron Lett. 1993, 34, 331; acromelic acid E: (i) Ref. 4h.
4. For pertinent reviews for the synthesis of the kainoid amino acids, see: (a) Hashimoto, K.; Shirahama, H. Trends Org. Chem. 1991, 2, 1;
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