Reactions of the Butyllithiums with Tertiary Oligoethylenepolyamines

Author:

Luitjes Hendrikus,Schakel Marius,Aarnts Maxim P,Schmitz Robert F,de Kanter Franciscus J.J,Klumpp Gerhard W

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference32 articles.

1. For recent examples and surveys of earlier literature, see: Endo, K., and Otsu, T. Makromol. Chem., Rapid Commun. 1993, 14, 1; Crassous, G., Abadie, M., and Schue, F., European Polymer Journal 1979, 15, 747.

2. Many examples involving N,N,N′,N′-tetramethylethylenediamine (TMEDA, 1-CH3) are cited and discussed in: Collum, D.B. Acc. Chem. Res. 1992, 10, 448.

3. Mechanisms of aromatic lithiation

4. (a) n-BuLi, s-BuLi (50 °C), Smith, W.N. Adv. Chem. Ser. 1974, 130, 23;

5. (b) t-BuLi (23 °C), Köhler, F.; Hertkorn, N.; Blümel, J. Chem. Ber. 1987, 120, 2081; X-ray structure of a mixed aggregate RLi·1-Li·1-H: Harder, S.; Lutz, M. Organometallics 1994, 131, 5173.

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