Synthesis of 2′-α-C-allenyl-2′-deoxyuridine: An analogue of 2′-azido-2′-deoxyuridine, known inhibitor of ribonucleotide diphosphate reductase (RDPR)
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference16 articles.
1. PROTEIN RADICAL INVOLVEMENT IN BIOLOGICAL CATALYSIS?
2. Alternative model for mechanism-based inhibition of Escherichia coli ribonucleotide reductase by 2'-azido-2'-deoxyuridine 5'-diphosphate
3. Mechanism of inactivation of Escherichia coli and Lactobacillus leichmannii ribonucleotide reductases by 2'-chloro-2'-deoxynucleotides: evidence for generation of 2-methylene-3(2H)-furanone
4. Mechanism of inactivation of Escherichia coli ribonucleotide reductase by 2'-chloro-2'-deoxyuridine 5'-diphosphate: evidence for generation of a 2'-deoxy-3'-ketonucleotide via a net 1,2 hydrogen shift
5. Products of the inactivation of ribonucleoside diphosphate reductase from Escherichia coli with 2'-azido-2'-deoxyuridine 5'-diphosphate
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2. ChemInform Abstract: Synthesis of 2′-α-C-Allenyl-2′-deoxyuridine: An Analogue of 2′-Azido-2′-deoxyuridine, Known Inhibitor of Ribonucleotide Diphosphate Reductase (RDPR).;ChemInform;2010-06-13
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