A novel synthesis of AZT
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference27 articles.
1. An efficient total synthesis of 3′-azido-3′-deoxythymidine (AZT) and 3′-azido-2′,3′-dideoxyuridine (AZDDU, CS-87) from D-mannitol
2. Chu, C. K. University of Georgia Research Fundation, Inc., PCT Int. Appl. WO 9 001 492, 22 Feb 1990, US Appl. 227, 163, 02 Aug 1988, p 44.
3. Aminonuclosides and Their Derivatives; XII1. A New Synthesis of 1-O-Methyl-3-azido-2,3-dideoxy-D-ribofuranose
4. Methyl 5-O--butyldiphenylsilyl-2-deoxy-D-threo-pentofuranoside; an approach to the syntesis of 3′-substituted-2′,3′-dideoxynucleosides including 3′-azido-3′-deoxythymidine and of 3′-substituted-2′,3′-dideoxy-C-nucleosides
5. Methyl 5-0--butyldiphenylsilyl-2-deoxy-α β -d--pentofuranoside as a divergent intermediate for the synthesis of 3'-substituted-2',3'-dideoxynucleosides: synthesis of 3'-azido-3'-deoxythymidine, 3'-deoxy-3'-fluorothymidine and 3'-cyano-3'-deoxythymidine.
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