Farnesyl chain modification of squalene synthase inhibitor benzylfarnesylamine: Conversion to the terminal bis(trifluoromethyl) derivative
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference21 articles.
1. Zaragozic acids: a family of fungal metabolites that are picomolar competitive inhibitors of squalene synthase.
2. Squalestatin 1, a potent inhibitor of squalene synthase, which lowers serum cholesterol in vivo.
3. Isoprenyl phosphinylformates: new inhibitors of squalene synthetase
4. Squalene synthetase, inhibition by ammonium analogs of carbocationic intermediates in the conversion of presqualene diphosphate to squalene
5. Synthesis and characterization of aza analog inhibitors of squalene and geranylgeranyl diphosphate synthases.
Cited by 6 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Comprehensive Structure–Activity Relationship Studies of Cepafungin Enabled by Biocatalytic C–H Oxidations;ACS Central Science;2023-01-27
2. ChemInform Abstract: Farnesyl Chain Modification of Squalene Synthase Inhibitor Benzylfarnesylamine: Conversion to the Terminal Bis(trifluoromethyl) Derivative.;ChemInform;2010-08-19
3. Synthesis of 2′,3′-dihydrosolanesyl analogues of β-d-arabinofuranosyl-1-monophosphoryldecaprenol with promising antimycobacterial activity;Tetrahedron Letters;2007-01
4. The biosynthesis of steroids and triterpenoids;Natural Product Reports;1998
5. Natural and Unnatural Terpenoid Precursors of Insect Juvenile Hormone;The Journal of Organic Chemistry;1997-05-01
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3