A new approach for the synthesis of 3′-deoxy-3′-C-formyl-ribonucleosides and the synthesis of alternating methylene(methylimino) linked phosphodiester backbone oligonucleotides with 2′-OH and 2′-OMe groups-Reference-Cited by-同舟云学术

A new approach for the synthesis of 3′-deoxy-3′-C-formyl-ribonucleosides and the synthesis of alternating methylene(methylimino) linked phosphodiester backbone oligonucleotides with 2′-OH and 2′-OMe groups

Published:2000-12 Issue:51 Volume:41 Page:9967-9971
ISSN:0040-4039
Container-title:Tetrahedron Letters
language:en
Short-container-title:Tetrahedron Letters

Author:

Prhavc Marija,Just* George,Bhat Balkrishen,Cook P.Dan,Manoharan Muthiah

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference27 articles.

1. Oligonucleosides: synthesis of a novel methylhydroxylamine-linked nucleoside dimer and its incorporation into antisense sequences

2. Synthesis of Novel Nucleic Acid Mimics via the Stereoselective Intermolecular Radical Coupling of 3‘-Iodo Nucleosides and Formaldoximes1

3. Concept, Discovery and Development of MMI Linkage: Story of a Novel Linkage: for Antisense Constructs

4. For a recent review describing the role of 2′-OH in RNA structure, see: Batey, R. T.; Rambo, R. P.; Doudna, J. A. Angew. Chem., Int. Ed. 1999, 38, 2327.

5. Swayze, E. E.; Sanghvi, Y. S. Synlett 1997, 859.

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4. ChemInform Abstract: A New Approach for the Synthesis of 3′-Deoxy-3′-C-formyl-ribonucleosides and the Synthesis of Alternating Methylene(methylimino) Linked Phosphodiester Backbone Oligonucleotides with 2′-OH and 2′-OMe Groups.;ChemInform;2001-03-13