iPSC-based drug screening for Huntington׳s disease

Author:

Zhang Ningzhe,Bailus Barbara J.,Ring Karen L.,Ellerby Lisa M.

Publisher

Elsevier BV

Subject

Developmental Biology,Neurology (clinical),Molecular Biology,General Neuroscience

Reference136 articles.

1. Available from: 〈http://www.cirm.ca.gov/our-progress/awards/use-human-ipsc-derived-neurons-huntington%E2%80%99s-disease-patients-develop-novel%3E〉 [cited].

2. Introduction: cell-based assays for high-throughput screening;An;Methods Mol. Biol.,2009

3. Polyglutamine disease modeling: epitope based screen forhomologous recombination using CRISPR/Cas9 System;An;PLoS Curr,2014

4. Genetic correction of Huntington׳s disease phenotypes in induced pluripotent stem cells;An;Cell Stem Cell.,2012

5. Mutations of the homeobox genes Dlx-1 and Dlx-2 disrupt the striatal subventricular zone and differentiation of late born striatal neurons;Anderson;Neuron,1997

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