Extracellular α-crystallin protects astrocytes from cell death through activation of MAPK, PI3K/Akt signaling pathway and blockade of ROS release from mitochondria

Author:

Zhu Zhihui,Li Rongyu,Stricker Rolf,Reiser Georg

Funder

Deutsche Forschungsgemeinschaft

Publisher

Elsevier BV

Subject

Developmental Biology,Neurology (clinical),Molecular Biology,General Neuroscience

Reference60 articles.

1. Peroxisome proliferator-activated receptor β/δ (PPARbeta/delta) protects against ceramide-induced cellular toxicity in rat brain astrocytes and neurons by activation of ceramide kinase.;Aleshin;Mol. Cell. Neurosci.,2014

2. Differential protective activity of αA- and αB-crystallin in lens epithelial cells;Andley;J. Biol. Chem.,2000

3. Induction of apoptosis by staurosporine involves the inhibition of expression of the major cell cycle proteins at the G2/m checkpoint accompanied by alterations in Erk and Akt kinase activities;Antonsson;Anticancer Res.,2009

4. Systemic augmentation of αB-crystallin provides therapeutic benefit twelve hours post-stroke onset via immune modulation;Arac;Proc. Natl. Acad. Sci. U.S.A.,2011

5. HspB1, HspB5 and HspB4 in human cancers: potent oncogenic role of some of their client proteins;Arrigo;Cancers (Basel),2014

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