Attenuation of morphine tolerance by intrathecal gabapentin is associated with suppression of morphine-evoked excitatory amino acid release in the rat spinal cord

Author:

Lin Jui-An,Lee Meei-Shyuan,Wu Ching-Tang,Yeh Chun-Chang,Lin Shinn-Long,Wen Zhi-Hong,Wong Chih-Shung

Publisher

Elsevier BV

Subject

Developmental Biology,Clinical Neurology,Molecular Biology,General Neuroscience

Reference43 articles.

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2. Modulation of opioid analgesia, tolerance and dependence by Gs-coupled, GM1 ganglioside-regulated opioid receptor functions;Crain;Trends. Pharmacol. Sci.,1998

3. The role of NMDA and non-NMDA excitatory amino acid receptors in the excitation of primate spinothalamic tract neurons by mechanical, chemical, thermal, and electrical stimuli;Dougherty;J. Neurosci.,1992

4. Gabapentin enhances the analgesic effect of morphine in healthy volunteers;Eckhardt;Anesth. Analg.,2000

5. Evaluation of gabapentin and S-(+)-3-isobutylgaba in a rat model of postoperative pain;Field;J. Pharmacol. Exp. Ther.,1997

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