N2L, a novel lipoic acid-niacin dimer, attenuates ferroptosis and decreases lipid peroxidation in HT22 cells

Author:

Peng Weijia,Zhu Zeyu,Yang Yang,Hou Jiawei,Lu Junfeng,Chen Chen,Liu FangORCID,Pi Rongbiao

Funder

Guangdong Provincial Department of Science and Technology

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

General Neuroscience

Reference61 articles.

1. Deferoxamine treatment prevents post-stroke vasoregression and neurovascular unit remodeling leading to improved functional outcomes in type 2 male diabetic rats: role of endothelial ferroptosis;Abdul;Transl. Stroke Res.,2020

2. Mitochondria and lipid peroxidation in the mechanism of neurodegeneration: finding ways for prevention;Angelova;Med. Res. Rev.,2021

3. Resolving the paradox of ferroptotic cell death: Ferrostatin-1 binds to 15LOX/PEBP1 complex, suppresses generation of peroxidized ETE-PE, and protects against ferroptosis;Anthonymuthu;Redox Biol.,2020

4. Regional brain iron associated with deterioration in Alzheimer’s disease: a large cohort study and theoretical significance;Ayton;Alzheimers Dement.,2021

5. Loss of ferroportin induces memory impairment by promoting ferroptosis in Alzheimer’s disease;Bao;Cell Death Differ.,2021

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