Both PI3K/Akt and ERK1/2 pathways participate in the protection by dexmedetomidine against transient focal cerebral ischemia/reperfusion injury in rats-Reference-Cited by-同舟云学术

Both PI3K/Akt and ERK1/2 pathways participate in the protection by dexmedetomidine against transient focal cerebral ischemia/reperfusion injury in rats

Published:2013-02 Issue: Volume:1494 Page:1-8
ISSN:0006-8993
Container-title:Brain Research
language:en
Short-container-title:Brain Research

Author:

Zhu Yong-Man,Wang Can-Can,Chen Long,Qian Ling-Bo,Ma Lei-Lei,Yu Jing,Zhu Man-Hua,Wen Chuan-Yun,Yu Li-Na,Yan Min

Publisher

Elsevier BV

Subject

Developmental Biology,Neurology (clinical),Molecular Biology,General Neuroscience

Reference31 articles.

1. MEK1 protein kinase inhibition protects against damage resulting from focal cerebral ischemia;Alessandrini;Proc. Natl. Acad. Sci. USA,1999

2. Pharmacokinetic-pharmacodynamic characterization of the cardiovascular, hypnotic, EEG and ventilatory responses to dexmedetomidine in the rat;Bol;J. Pharmacol. Exp. Ther.,1997

3. Two different molecular mechanisms underlying progesterone neuroprotection against ischemic brain damage;Cai;Neuropharmacology,2008

4. The phosphoinositide 3-kinase pathway;Cantley;Science,2002

5. Strain-specific immunity may drive adaptive polymorphism in the merozoite surface protein 1 of the rodent malaria parasite Plasmodium chabaudi;Cheesman;Infect. Genet. Evol.,2009

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1. Dexmedetomidine alleviates cerebral ischemia-reperfusion injury via inhibiting autophagy through PI3K/Akt/mTOR pathway;Journal of Molecular Histology;2023-04-26

2. PD98059 protects SH-SY5Y cells against oxidative stress in oxygen–glucose deprivation/reperfusion;Translational Neuroscience;2023-01-01

3. Dexmedetomidine suppresses the isoflurane-induced neurological damage by upregulating Heme Oxygenase-1 via activation of the mitogen-activated protein kinase kinase 1/extracellular regulated protein kinases 1/nuclear factor erythroid 2-related factor 2 axis in aged rats;Chemico-Biological Interactions;2022-11

4. Dexmedetomidine attenuates renal ischemia–reperfusion injury through activating PI3K / Akt‐eNOS signaling via α ₂ adrenoreceptors in renal microvascular endothelial cells;The FASEB Journal;2022-10-17

5. Dexmedetomidine Inhibits NF-κB-Transcriptional Activity in Neurons Undergoing Ischemia-Reperfusion by Regulating O-GlcNAcylation of SNW1;Journal of Neuropathology & Experimental Neurology;2022-07-11