Efficient RNA interference-based knockdown of mutant torsinA reveals reversibility of PERK-eIF2α pathway dysregulation in DYT1 transgenic rats in vivo-Reference-Cited by-同舟云学术

Efficient RNA interference-based knockdown of mutant torsinA reveals reversibility of PERK-eIF2α pathway dysregulation in DYT1 transgenic rats in vivo

Published:2019-03 Issue: Volume:1706 Page:24-31
ISSN:0006-8993
Container-title:Brain Research
language:en
Short-container-title:Brain Research

Author:

Beauvais Genevieve,Watson Jaime L.,Aguirre Jose A.,Tecedor Luis,Ehrlich Michelle E.,Gonzalez-Alegre Pedro

Funder

Department of Defense

National Institutes of Health

International Mobility, Programme Salvador de Madariaga

Publisher

Elsevier BV

Subject

Developmental Biology,Clinical Neurology,Molecular Biology,General Neuroscience

Reference43 articles.

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3. Disruption of protein processing in the endoplasmic reticulum of DYT1 knock-in mice implicates novel pathways in dystonia pathogenesis;Beauvais;J. Neurosci.,2016

4. Exploring the interaction between eIF2alpha dysregulation, acute endoplasmic reticulum stress and DYT1 dystonia in the mammalian brain;Beauvais;Neuroscience,2018

5. Translational control by eIF2alpha in neurons: beyond the stress response;Bellato;Cytoskeleton (Hoboken),2016

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2. Allele-specific targeting of mutant TOR1A by the compact CRISPR/NmCas9 system in DYT1 dystonia with high fidelity;2024-04-23

3. The integrated stress response pathway and neuromodulator signaling in the brain: lessons learned from dystonia;Journal of Clinical Investigation;2024-04-01

4. DYT-TOR1A dystonia: an update on pathogenesis and treatment;Frontiers in Neuroscience;2023-08-10

5. Dystonia Linked to EIF4A2 Haploinsufficiency: A Disorder of Protein Translation Dysfunction;Movement Disorders;2023-07-23