The main mechanism associated with progression of glucose intolerance in older patients with cystic fibrosis is insulin resistance and not reduced insulin secretion capacity

Author:

Colomba JohannORCID,Boudreau ValérieORCID,Lehoux-Dubois Catherine,Desjardins Katherine,Coriati Adèle,Tremblay François,Rabasa-Lhoret Rémi

Funder

Canadian Cystic Fibrosis Foundation

J-A DeSève Diabetes research chair

Canadian Institute of Health Research

Fonds de recherche du Québec – Santé (FRQS) scholarships

Cystic Fibrosis Canada Fellowship

Publisher

Elsevier BV

Subject

Pulmonary and Respiratory Medicine,Pediatrics, Perinatology, and Child Health

Reference45 articles.

1. Patient registry. Annual data report 2001;Cystic fibrosis foundation,2002

2. Effects of ageing on insulin secretion and action;Moller;Horm Res,2003

3. The critical role of metabolic pathways in aging;Barzilai;Diabetes,2012

4. Nutritional status and body fat distribution in children and adolescentes with cystic fibrosis;Chaves;Cien Saude Colet,2015

5. Variation of glucose tolerance in adult patients with cystic fibrosis: what is the potential contribution of insulin sensitivity?;Boudreau;J Cyst Fibros,2016

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