Pitavastatin ameliorates autoimmune neuroinflammation by regulating the Treg/Th17 cell balance through inhibition of mevalonate metabolism

Author:

Prado D.S.,Damasceno L.E.A.,Sonego A.B.,Rosa M.H.,Martins T.V.,Fonseca M.D.M.,Cunha T.M.,Cunha F.Q.,Alves-Filho J.C.

Funder

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Fundação de Amparo à Pesquisa do Estado de São Paulo

Publisher

Elsevier BV

Subject

Pharmacology,Immunology,Immunology and Allergy

Reference61 articles.

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3. T cells in multiple sclerosis and experimental autoimmune encephalomyelitis;Fletcher;Clin. Exp. Immunol.,2010

4. T cell response in experimental autoimmune encehphalomyelitis (EAE): role of self and cross-reactive antigens in shaping, tuning, and regulating the autopathogenic T cell repertoire;Kuchroo;Annu. Rev. Immunol.,2002

5. In vivo immunomodulation by monoclonal anti-CD4 antibody. II. Effect on T cell response to myelin basic protein and experimental allergic encephalomyelitis;Sriram;J. Immunol.,1988

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