Isodeoxyelephantopin, a sesquiterpene lactone from Elephantopus scaber Linn., inhibits pro-inflammatory mediators’ production through both NF-κB and AP-1 pathways in LPS-activated macrophages

Author:

Han Yixin,Li Ximeng,Zhang Xiaoyu,Gao Yuan,Qi Ruijuan,Cai Runlan,Qi Yun

Funder

CAMS Innovation Fund for Medical Sciences

National Natural Science Foundation of China

Drug Innovation Major Project

Publisher

Elsevier BV

Subject

Pharmacology,Immunology,Immunology and Allergy

Reference49 articles.

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3. Lipopolysaccharide (LPS) from the cellular wall of Gram-negative bacteria, also known as endotoxin, is a key molecule in the pathogenesis of sepsis and septic shock;Ronco;Preface, Blood Purif.,2014

4. CD11c+ alveolar macrophages are a source of IL-23 during lipopolysaccharide-induced acute lung injury;Bosmann;Shock,2013

5. Innate immune recognition in infectious and noninfectious diseases of the lung;Opitz;Am. J. Respir. Crit. Care Med.,2010

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