Virulizin®, a novel immunotherapy agent, stimulates TNFα expression in monocytes/macrophages in vitro and in vivo

Author:

Li Hui,Cao Ming Y.,Lee Yoon,Benatar Tania,Lee Vivian,Feng Ningping,Gu Xiaoping,Liu Pu,Jin Hongnan,Wang Ming,Der Sandy,Lightfoot Jeff,Wright Jim A.,Young Aiping H.

Publisher

Elsevier BV

Subject

Pharmacology,Immunology,Immunology and Allergy

Reference45 articles.

1. Antitumor activity of Virulizin, a novel biological response modifier (BRM) in a panel of human pancreatic cancer and melanoma xenografts;Feng;Cancer Chemother Pharmacol,2003

2. Preclinical efficacy of Virulizin in human breast, ovarian and prostate tumor models;Du;Anticancer Drugs,2003

3. Macrophages play a critical role in the anti-tumor activity of Virulizin;Du;Int J Oncol,2003

4. NK cell activation and tumor infiltration are involved in the antitumor mechanism of Virulizin;Cao;Cancer Immunol Immunother,2005

5. Virulizin® — a review of its antineoplastic activity;Ferdinandi;Expert Opin Investig Drugs,1999

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