ASIC1a promotes synovial invasion of rheumatoid arthritis via Ca2+/Rac1 pathway

Author:

Niu Ruowen,Hang Xiaoyu,Feng Yubin,Zhang Yihao,Qian Xuewen,Song Sujing,Wang Cong,Tao Jingjing,Peng Xiaoqing,Chen Feihu

Funder

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Pharmacology,Immunology,Immunology and Allergy

Reference33 articles.

1. Cytokine pathways and joint inflammation in rheumatoid arthritis;Choy;New Engl. J. Med.,2001

2. Synovial fibroblasts: key players in rheumatoid arthritis;Huber;Rheumatology,2006

3. uPAR promotes tumor-like biologic behaviors of fibroblast-like synoviocytes through PI3K/Akt signaling pathway in patients with rheumatoid arthritis;Liu;CellMol. Immunol.,2018

4. Tetrandrine inhibits migration and invasion of rheumatoid arthritis fibroblast-like synoviocytes through down-regulating the expressions of Rac1, Cdc42, and RhoA GTPases and activation of the PI3K/Akt and JNK signaling pathways;Lv;Chin J. Nat. Med.,2015

5. Oxymatrine exerts protective effects on osteoarthritis via modulating chondrocyte homoeostasis and suppressing osteoclastogenesis;Jiang;J. Cell. Mol. Med.,2018

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