PD-1 Receptor (+) T cells are associated with the efficacy of the combined treatment with regulatory t cells and rituximab in type 1 diabetes children via regulatory t cells suppressive activity amelioration

Author:

Zieliński Maciej,Sakowska Justyna,Iwaszkiewicz-Grześ Dorota,Gliwiński Mateusz,Hennig Matylda,Żalińska Magdalena,Wołoszyn-Durkiewicz Anna,Jaźwińska-Curyłło Anna,Kamińska Halla,Owczuk Radosław,Młynarski Wojciech,Jarosz-Chobot Przemysława,Bossowski Artur,Szadkowska AgnieszkaORCID,Fendler Wojciech,Beń-Skowronek Iwona,Chobot Agata,Myśliwiec Małgorzata,Siebert Janusz,Marek-Trzonkowska Natalia,Trzonkowski PiotrORCID

Funder

Horizon 2020

Medical Research Agency

Publisher

Elsevier BV

Reference40 articles.

1. Interactions between islets and regulatory immune cells in health and type 1 diabetes;Budd;Diabetologia.,2021

2. Nature vs. nurture: FOXP3, genetics, and tissue environment shape Treg function;Raugh;Front. Immunol.,2022

3. The need and benefit of immune monitoring to define patient and disease heterogeneity, mechanisms of therapeutic action and efficacy of intervention therapy for precision medicine in type 1 diabetes;Roep;Front. Immunol.,2023

4. Defining a cure for type 1 diabetes: a call to action;Roep;lancet. Diabetes. Endocrinol.,2021

5. An anti-CD3 antibody, teplizumab, in relatives at risk for type 1 diabetes;Herold;N. Engl. J. Med.,2019

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