TRIM65 knockout inhibits the development of HCC by polarization tumor-associated macrophages towards M1 phenotype via JAK1/STAT1 signaling pathway

Author:

Jiang Meixiu,Wang Dan,Su Ning,Lou Weiming,Chen Yinni,Yang Haiyan,Chen Chen,Xi Feiyang,Chen Yuanli,Deng Libin,Tang XiaoliORCID

Funder

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Pharmacology,Immunology,Immunology and Allergy

Reference57 articles.

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2. TRIM65 triggers beta-catenin signaling via ubiquitylation of Axin1 to promote hepatocellular carcinoma;Yang;J. Cell Sci.,2017

3. Challenges and opportunities in the clinical development of immune checkpoint inhibitors for hepatocellular carcinoma;Flynn;Hepatology.,2019

4. The tumor microenvironment innately modulates cancer progression;Hinshaw;Cancer. Res.,2019

5. Tumor cells induce LAMP2a expression in tumor-associated macrophage for cancer progression;Wang;EBioMedicine,2019

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