Stachydrine ameliorates isoproterenol-induced cardiac hypertrophy and fibrosis by suppressing inflammation and oxidative stress through inhibiting NF-κB and JAK/STAT signaling pathways in rats

Author:

Zhao Lingling,Wu Dawei,Sang Mengru,Xu Yiming,Liu Zhaoguo,Wu Qinan

Funder

National Natural Science Foundation of China

National Public Service Industry

National Public Health Industry

Jiangsu Province

Publisher

Elsevier BV

Subject

Pharmacology,Immunology,Immunology and Allergy

Reference45 articles.

1. Epigenetic therapy for the treatment of hypertension-induced cardiac hypertrophy and fibrosis;Watson;J. Cardiovasc. Pharmacol. Ther.,2016

2. Inflammation and echocardiographic parameters of ventricular hypertrophy in a cohort with preserved cardiac function;Medenwald;Open Heart,2014

3. Celecoxib prevents pressure overload-induced cardiac hypertrophy and dysfunction by inhibiting inflammation, apoptosis and oxidative stress;Zhang;J. Cell. Mol. Med.,2016

4. Simvastatin prevents isoproterenol-induced cardiac hypertrophy through modulation of the JAK/STAT pathway;Al-Rasheed;Drug Des. Devel. Ther.,2015

5. Gambogic acid suppresses pressure overload cardiac hypertrophy in rats;Liu;Am. J. Cardiovasc. Dis.,2013

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