S-adenosylmethionine inhibits the activated phenotype of human hepatic stellate cells via Rac1 and Matrix metalloproteinases

Author:

Zhang Feng,Zhuge Yu-Zheng,Li Yu-Jiang,Gu Jian-Xiang

Publisher

Elsevier BV

Subject

Pharmacology,Immunology,Immunology and Allergy

Reference29 articles.

1. Mechanisms of hepatic fibrogenesis;Friedman;Gastroenterology,2008

2. Changes in the expression of methionine adenosyltransferase genes and S-adenosylmethionine homeostasis during hepatic stellate cell activation;Ramani;Hepatology,2010

3. Effect of S-adenosyl-l-methionine on the activation, proliferation and contraction of hepatic stellate cells;Matsui;Eur J Pharmacol,2005

4. DLPC and SAMe combined prevent leptin-stimulated TIMP-1 production in LX-2 human hepatic stellate cells by inhibiting HO-mediated signal transduction;Cao;Liver Int,2006

5. S-adenosyl-l-methionine inhibits collagen secretion in hepatic stellate cells via increased ubiquitination;Thompson;Liver Int,2011

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