High throughput screening identifies auranofin and pentamidine as potent compounds that lower IFN-γ-induced Nitric Oxide and inflammatory responses in mice: DSS-induced colitis and Salmonella Typhimurium-induced sepsis

Author:

Chattopadhyay AvikORCID,Joseph Joel P.ORCID,Jagdish SirishaORCID,Chaudhuri Somak,Ramteke Nikita S.,Karhale Aagosh Kishore,Waturuocha Uchenna,Saini Deepak Kumar,Nandi DipankarORCID

Funder

Department of Biotechnology, Ministry of Science and Technology, India

Department of Science and Technology, Ministry of Science and Technology, India

Indian Institute of Science

Science and Engineering Research Board

Publisher

Elsevier BV

Subject

Pharmacology,Immunology,Immunology and Allergy

Reference72 articles.

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2. Interferon-gamma induced cell death: regulation and contributions of nitric oxide, cJun N-terminal kinase, reactive oxygen species and peroxynitrite;Rakshit;Biochim. Biophys. Acta - Mol. Cell Res.,1843

3. Nitric oxide is not just blowing in the wind;Ignarro;Br. J. Pharmacol.,2019

4. Calcium-mediated signaling and calmodulin-dependent kinase regulate hepatocyte inducible nitric oxide synthase expression;Zhang;J. Surg. Res.,2015

5. Interferon gamma activated macrophages kill mycobacteria by nitric oxide induced apoptosis;Herbst;PLoS One.,2011

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