Impact of pharmacodynamic variability on drug delivery1

Author:

Levy G

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference19 articles.

1. Population pharmacodynamics: Strategies for concentration- and effect-controlled clinical trials;Ebling;Ann. Pharmacother.,1996

2. Relationship between concentration and anticoagulant effect of heparin in plasma of normal subjects: Magnitude and predictability of interindividual differences;Whitfield;Clin. Pharmacol. Ther.,1980

3. G. Levy, Variability in animal and human pharmacodynamic studies, in: M. Rowland, L.B. Sheiner, J.-L. Steimer (Eds.), Variability in Drug Therapy: Description, Estimation, and Control. Raven Press, New York, 1985, pp. 125–138.

4. Kinetics of pharmacologic effects;Levy;Clin. Pharmacol. Ther.,1966

5. Feasibility of effect-controlled clinical trials of drugs with pharmacodynamic hysteresis using sparse data;Ebling;Pharm. Res.,1996

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