RAB5A effect on metastasis of hepatocellular carcinoma cell line via altering the pro-invasive content of exosomes

Author:

Gorji-bahri Gilar,Moghimi Hamid Reza,Hashemi Atieh

Funder

Iran National Elites Foundation

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Molecular Biology,Pathology and Forensic Medicine

Reference20 articles.

1. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries;Bray;CA Cancer J. Clin.,2018

2. Overexpression of Rab5a promotes hepatocellular carcinoma cell proliferation and invasion via FAK signaling pathway;Geng;Tumour Biol.,2016

3. ExomiRs: a novel strategy in cancer diagnosis and therapy;Gorji-Bahri;Curr. Gene Ther.,2018

4. RAB5A is associated with genes involved in exosome secretion: integration of bioinformatics analysis and experimental validation;Gorji-bahri;J. Cell. Biochem.,2020

5. Atg5 disassociates the V1V0-ATPase to promote exosome production and tumor metastasis independent of canonical macroautophagy;Guo;Dev. Cell,2017

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