HDAC1 overexpression independently predicts biochemical recurrence and is associated with rapid tumor cell proliferation and genomic instability in prostate cancer

Author:

Burdelski Christoph,Ruge Oliver M.,Melling Nathaniel,Koop Christina,Simon RonaldORCID,Steurer Stefan,Sauter Guido,Kluth Martina,Hube-Magg Claudia,Minner Sarah,Wittmer Corinna,Wilczak Waldemar,Hinsch Andrea,Lebok Patrick,Izbicki Jakob R.,Heinzer Hans,Graefen Markus,Huland Hartwig,Schlomm Thorsten,Krech Till

Funder

Universitätsklinikum Hamburg-Eppendorf

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Molecular Biology,Pathology and Forensic Medicine

Reference53 articles.

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2. CHD1 is a 5q21 tumor suppressor required for ERG rearrangement in prostate cancer;Burkhardt;Cancer Res.,2013

3. Suberoylanilide hydroxamic acid, an inhibitor of histone deacetylase, suppresses the growth of prostate cancer cells in vitro and in vivo;Butler;Cancer Res.,2000

4. ETS gene fusions in prostate cancer;Clark;Nat. Rev. Urol.,2009

5. Combinatorial antitumor effect of HDAC and the PI3K-Akt-mTOR pathway inhibition in a Pten deficient model of prostate cancer;Ellis;Oncotarget,2013

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